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Dr Deep Jyoti Bhuyan

PhD, MSc, BSc
Senior Research Fellow - Healthy Ageing: Therapeutic Potential of Natural Products 

NICM Health Research Institute, Western Sydney University

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Dr Bhuyan is a Senior Research Fellow, Global Challenge Lead and SDG 3 Research Cluster Lead at WSU. He is also the HDR Coordinator of NICM Health Research Institute (NICM HRI). At NICM HRI, he oversees The GutBiotics Lab, investigating the correlation between gut microbial metabolites (postbiotics) and human health. Dr Bhuyan's research group studies the therapeutic potential of postbiotics and phytochemicals from Australian native plants, focusing on their molecular mechanisms of action against cancer and the development of natural product-based therapies for bacterial and viral diseases.

 

He was recently appointed as the WSU Global Challenge Lead for the Fostering Healthy Communities Program. He works closely with two academics from the Schools of Business and Health to strengthen collaboration among relevant schools, institutes, and industry partners in health and medicine research and education. As part of this program, he, along with his two fellow leads, spearheads WSU as the lead on the United Nations' SDG 3 (Health and Well-being), supported by the International Association of Universities and UNESCO, guiding other international universities across five continents in SDG 3.

 

In 2023, Dr Bhuyan was appointed NICM HRI's International Engagement Coordinator, tasked with strengthening the institute's collaboration with India through research partnerships, policy development, and scholar exchange programs. Subsequently, he took on the role of NICM HRI’s HDR Coordinator after briefly acting as the HDR Director. He works closely with the HDR Director to streamline candidature processes and cultivate a supportive environment for over 40 HDR students.

 

Dr Bhuyan earned his PhD from the University of Newcastle, focusing on the anticancer and antimicrobial properties of phenolic compounds and antioxidants in Australian Eucalyptus species at the molecular level. Government, industry, and university grants, including funding from various organisations, support his research at NICM HRI. He has also cultivated active collaborations with more than 40 international organisations globally.

 

Before coming to Australia, Dr Bhuyan held the position of Senior Research Fellow in probiotic food development at Assam Agricultural University, overseeing projects funded by the Indian Council of Agricultural Research. With a background in applied microbiology and cancer biology, he has extensive experience in government and industry-funded research projects in food chemistry, microbiology, and pharmacology in India and Australia.

 

Dr Bhuyan has produced several peer-reviewed journal articles and invited book chapters, and presented his research at national and international conferences. He has also written for The Conversation on postbiotics, which has been featured in television and radio interviews and has received global media coverage. His contributions and commitment to the research community are recognised by his involvement with various external committees and advisory boards, including the NHMRC Grant Review Working Committee and FOODiQ Global. Currently, he provides supervision and guidance to 12 PhD and MRes students while actively promoting science communication and STEM education on social media.

Education

2008 Bachelor of Science Biotechnology, Bangalore University, India

2010 Master of Science Applied Microbiology, VIT University, India

2018 PhD in Food Science, The University of Newcastle, Australia

Research Focus

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01

Gut Microbiota

How does gut microbiota affect the availability of nutrients? What is the role of gut microbiota-based strategies in diseases such as cancer, diabetes, and metabolic syndrome?

Implementation of gut microbiota-derived postbiotics in cancer therapy and healthy ageing and understanding their molecular mechanisms of action using state-of-the-art techniques.

02

Postbiotics

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Impact of phytochemicals and antioxidants, especially from Australian native plants and foods, on human health. Can fermentation improve the bioavailability of these phytochemicals and antioxidants?

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03

Phytochemicals and Antioxidants

Understanding how postbiotics and phytochemicals interact with standard drugs using advanced mathematical models and molecular assays.

04

Synergistic Mechanisms

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05

Combination Therapy

Can we combine existing therapies for infectious diseases and cancer to improve efficacy (i.e., 1+1=3)?

Isolation and molecular characterisation of anticancer agents from sources such as Australian native plants and gut microbial communities.

06

Anticancer agents

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Antiviral, antibacterial and antifungal properties of bioactive compounds and their interactions with standard antimicrobial agents.

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07

Antimicrobial Agents

Affiliations

2023 Joint Academic Microbiology Seminars Society

2023 Universal Scientific Education and Research Network

2023 Polyphenols Applications

2023 Committee Member, Joint Academic Microbiology Seminars Society

2022 Committee Member, NHMRC – Ideas Grants Peer Review Working Committee 2022

2022 International Society for Traditional, Complementary and Integrative Medicine Research

2020 NSW Cardiovascular Research Network, National Heart Foundation

2019 The Good Practice In Traditional Chinese Medicine Research Association

2017 Pharmacological Society of Singapore

2016 Institute of Food Technologists, Chicago, USA

2015 Australian Society of Medical Research

2014 Hunter Medical Research Institute

2014 Pancreatic Cancer Research Group, School of Environmental and Life Sciences, University of Newcastle, Australia

2010 Defence Research and Development Organisation, Ministry of Defence, India

Invited Scientific Expert, Hort Innovation and FOODiQ Global

Global Advisory Board Member, ViGA

Guest Editor, Frontiers in Nutrition

Guest Editor, Journal of Ayurveda and Integrative Medicine

Review Board Member, Cancers, MDPI

Review Board Member, Microorganisms, MDPI

Committee Member, Western Sydney University Microbiology Interest Society

Committee Member, Western Sydney University Microbiome Interest Group

Committee Member, National Science Centre Poland, European Commission

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